2006 Mercedes-Benz E 350 Recalls, Problems & Safety Rating

4 safety recalls on file

The 2006 Mercedes-Benz E 350 has 4 safety recalls on file with NHTSA.

Owners have filed 400 complaints with NHTSA, including 14 crashes, 9 fires, 18 injuries.

The most-reported problem area is Fuel/Propulsion System (144 reports).

4Recalls
400Owner complaints
14Crashes reported
n/aNHTSA safety rating
Is the repair still open on your E 350?

A recall covers specific vehicles. Your VIN shows whether yours still needs the free repair.

2006 Mercedes-Benz E 350 recalls

Sunroof Glass Can Detach and Become a Road Hazard

Recall 24V874Nov 19, 202433,456 vehicles affected

The glass sunroof panel on certain Mercedes-Benz vehicles may not be properly secured, so it can detach while driving.

Sunroof Glass May Detach While Driving, Risking a Crash

Recall 22V954Dec 23, 2022131,653 vehicles affected

The glass sunroof panel on certain vehicles may not be properly secured to the vehicle, so it can come loose and detach while the car is being driven.

Sunroof Glass Can Detach While Driving, Creating Crash Risk

Recall 21V196Mar 19, 202111,356 vehicles affected

The bonding that holds the glass panel of the sunroof to its sliding frame can deteriorate over time.

Sunroof Glass Can Detach, Creating Road Hazard

Recall 19V918Dec 20, 2019747,928 vehicles affected

The adhesive bonding the sunroof glass panel to its sliding frame can deteriorate over time.

Most common 2006 Mercedes-Benz E 350 problems

Problem areas named in the 400 complaints owners filed with NHTSA.

Problem areaReports
Fuel/Propulsion System144
Fuel System, Gasoline80
Engine50
Service Brakes46
Power Train37
Engine And Engine Cooling22
Electrical System19
Air Bags14
Unknown Or Other10
Service Brakes, Hydraulic8

What owners report

2026-10-15, Service Brakes, Hydraulic
The contact owns a 2006 Mercedes-Benz E350. While driving at 30 MPH, a "Reduced Braking Power" warning message was displayed on the instrument panel followed by an audible alarm. The brake pedal travelled to the floorboard, resulting in a significant loss of braking functionality. Additionally, the vehicle became stuck in second gear, requiring the driver to pull over and have the vehicle towed to the residence. The consumer performed an OBD II scan, but no diagnostic trouble codes related to the brake failure were retrieved. The manufacturer was notified and confirmed that there were no active recalls associated with the failure. The failure mileage was approximately 151,000.
2026-09-23, Service Brakes, Hydraulic
The contact owns a 2006 Mercedes-Benz E-350. The contact stated that the sensotronic brake control warning was illuminated. The contact researched and found information about warranty coverage for 2006-2010 models with a 25-year warranty. The vehicle was taken to the dealer, who diagnosed that the main battery needed to be replaced but had not provided the repair. The vehicle was also taken to a certified mechanic who diagnosed that the brakes were failing and the computer system needed to be reset; however, the vehicle was not repaired. The contact stated that the belts were replaced. The message remained displayed. The failure mileage was 152,786.
2025-12-03, Service Brakes
Mercedes Benz issued a recall and extended a warranty on its 2003-2005 E Class SBC braking systems (recall # 2005110001) and extended the warranty to 25 years; the 2006 E Class models have the exact same SBC braking system but is not included in the recall. Mercedes needs to add the 2006 E Class models to recall # 2005110001. My 2006 is experiencing the same SBC issues the 2003-2005 models are known to have but because my vehicle is 2006 it is not covered by the extended warranty.
2025-10-23, Service Brakes, Hydraulic
The contact called on behalf of the owner of a 2006 Mercedes-Benz E350. The contact stated that while his mother was driving at an undisclosed speed and approaching a traffic light, the brake pedal was depressed; however, the brakes failed to function as intended. The brake pedal was depressed down to the floorboard. The contact's mother used the parking brake to stop the vehicle. The ABS warning light was illuminated. The vehicle was towed to the residence and then to an independent mechanic. The vehicle was diagnosed with Sensotronic Brake Control (SBC) system failure. The contact was informed that the Sensotronic Brake Control system needed to be replaced. The vehicle remained with the me
2025-10-21, Visibility
The contact's son owns a 2006 Mercedes-Benz E350. The contact stated that while his son was driving at an undisclosed speed, the sunroof detached and shattered on the roadway. The vehicle was not taken to the dealer or an independent mechanic. The vehicle was not repaired. After investigating the failure, the contact related the failure to NHTSA Campaign Number: 19V918000 (Visibility) and 22V954000 (Visibility); however, the VIN was included in the recalls, but the vehicle had been repaired in 2023 and 2025. The manufacturer was not notified of the failure. The failure mileage was 97,900.

2006 Mercedes-Benz E 350 questions

Does the 2006 Mercedes-Benz E 350 have any recalls?

Yes. NHTSA lists 4 safety recalls for the 2006 Mercedes-Benz E 350: Sunroof Glass Can Detach and Become a Road Hazard; Sunroof Glass May Detach While Driving, Risking a Crash; Sunroof Glass Can Detach While Driving, Creating Crash Risk; Sunroof Glass Can Detach, Creating Road Hazard. Recall repairs are normally free at an authorized dealer.

What are the most common problems with the 2006 Mercedes-Benz E 350?

Based on 400 owner complaints filed with NHTSA, the most-reported problem areas are Fuel/Propulsion System (144), Fuel System, Gasoline (80), Engine (50).

How do I check if a recall on my 2006 Mercedes-Benz E 350 has been fixed?

Enter your 17-character VIN in our VIN recall check. It shows open recalls that have not been repaired on your specific vehicle. Recall repairs are normally free at an authorized dealer.

Other Mercedes-Benz E 350 years

Other 2006 Mercedes-Benz models