The 2021 Ford E-350 has 6 safety recalls on file with NHTSA.
Owners have filed 22 complaints with NHTSA, including 1 crash.
The most-reported problem area is Engine (11 reports).
2021 Ford E-350 recalls
Engine cover can overheat and burn occupants
Certain 2021 Ford E-350 and E-450 vehicles received an incomplete software update under an earlier recall.
Loss of Power Steering and Brake Assist Can Raise Crash Risk
Some 2021-2022 Ford E-350 and E-450 vehicles with dual rear wheels may have an inadequate connection between the power steering pressure line and the brake hydroboost unit.
Loss of Power Steering and Brake Assist Can Raise Crash Risk
Some vans with dual rear wheels have a connection between the power steering pressure line and the brake Hydroboost unit that may not be adequate.
Engine Cover Can Overheat and Burn Driver or Passenger
Mispositioned insulation on the underside of the engine cover may allow the cover to get excessively hot.
Wiring Can Rub Frame, Risking Engine Stall and Lost Braking Control
A wire harness near the rear of these vehicles can contact the frame and become damaged.
Low Rear Axle Fluid Can Cause Driveshaft Separation
Rear axle differential fluid in these vehicles may fall below the minimum level.
Most common 2021 Ford E-350 problems
Problem areas named in the 22 complaints owners filed with NHTSA.
| Problem area | Reports |
|---|---|
| Engine | 11 |
| Steering | 7 |
| Service Brakes, Hydraulic | 7 |
| Unknown Or Other | 2 |
| Service Brakes | 2 |
| Traction Control System | 1 |
| Forward Collision Avoidance | 1 |
| Fuel System, Diesel | 1 |
What owners report
Engine misfire on a 2021 Ford E-350 cutaway, 7.3L V8, used for parcel delivery. The vehicle was delivered to Ford of Spartanburg (Ford dealership) for diagnosis. The vehicle is still out of service. Ford's diagnosis, Repair Order 593079, June 26, 2026: "WILL NEED TO REPLACE ALL SPARK PLUGS AND WIRES, WILL ALSO NEED TO REPLACED ALL COILS DUE TO MISFIRES ON ALMOST EVERY CYLINDER." The Ford service advisor wrote the same day: "The engine also has a misfire that is unrelated to the transmission concern." Ford quoted $4,376.35 for the ignition components and wrote: "AFTER REPAIRING TRANSMISSION WILL NEED TO DIAGNOSE ALL OTHER CONCERNS WITH VEHICLE, CANNOT DIAG ANYTHING AT MOMENT DUE TO NOT BEING
Engine failure on a 2021 Ford E-350 cutaway, 7.3L V8, used for parcel delivery. The vehicle was taken out of service and has not run since. Two diagnoses, both in writing. ACME Mobile Service, July 27, 2026, at 152,760 miles: "Found the #5 cylinder is completely disabled and dropped out. Truck will need a new motor." Ford of Spartanburg (Ford dealership), Repair Order 595835, August 25, 2026: "FOUND ENGINE IS KNOCKING, WILL NEED TO REPLACE MOTOR." Ford quoted $16,000.82 for a long-block replacement. The engine is available for inspection. This is the second engine failure on this VIN. In March 2023 at 83,575 miles the engine was rebuilt with new Ford parts (camshaft, sixteen lifters, rocker
fatal Camshaft and lifter failure requiring an engine replacement
Engine failure at 78,172, excess wear to the camshaft lobes and valve tappet surface. We have had 22 failures. There was a recall -24B27 for 2021 and 2022 models year for idle oil pressure. Most vans had 70 to 80k on them by the time we received a letter. Some engine have been changed twice. Ford has a serious problem and is not acknowledging it. Please help! Montachusett Regional Transit Authority , Fitchburg MA 01420
This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.
2021 Ford E-350 questions
Does the 2021 Ford E-350 have any recalls?
Yes. NHTSA lists 6 safety recalls for the 2021 Ford E-350: Engine cover can overheat and burn occupants; Loss of Power Steering and Brake Assist Can Raise Crash Risk; Loss of Power Steering and Brake Assist Can Raise Crash Risk; Engine Cover Can Overheat and Burn Driver or Passenger; Wiring Can Rub Frame, Risking Engine Stall and Lost Braking Control. Recall repairs are normally free at an authorized dealer.
What are the most common problems with the 2021 Ford E-350?
Based on 22 owner complaints filed with NHTSA, the most-reported problem areas are Engine (11), Steering (7), Service Brakes, Hydraulic (7).
How do I check if a recall on my 2021 Ford E-350 has been fixed?
Enter your 17-character VIN in our VIN recall check. It shows open recalls that have not been repaired on your specific vehicle. Recall repairs are normally free at an authorized dealer.